Welcome

It is a great pleasure to invite you to take part in the second addition of the International Symposium on Synthesis and Catalysis 2017 (ISySyCat2017) that will take place at the University of Evora in the historically recognized mediaeval city of Evora from September 5-8 2017. The first edition of IsySyCat that was held in the same venue in September 2015 was an enormous success with participants from 27 countries (http://isysycat.eventos.chemistry.pt/). The city of Evora besides its striking beauty, uniqueness and hospitality is steeped in history having being the home to the Romans, the Moors, Visigoth's and others, including the kings of Portugal. It has UNESCO world heritage, and this walled city is the location of a Roman temple, palaces and old cathedrals. The conference will take place in the old part of the University known as Colégio Espirito Santo which dates back to the 16th Century.

The conference will focus on key topics in contemporary organic and organometallic synthesis and catalysis, which are of relevance to both academic and industrial chemists alike. We anticipate a good mix of participants from academia and industry. This is reflected in the list of speakers hailing from both these domains from all over the world. We are eagerly looking forward to seeing you in Evora in September 2017.

Anthony Burke
Department of Chemistry and Centro de Química de Evora
University of Evora, Conference Chairman

Organization

Conference Chairman: Anthony Burke, University of Évora, Portugal.

Scientific Committee

Prof. Anthony Burke – University of Evora, Portugal
Prof. Paul Wender, University of Stanford, USA
Prof. Artur Silva – University of Aveiro, Portugal
Prof.a Lurdes Cristiano, University of the Algarve, Portugal
Prof. Narcisso Garrido – University of Salamanca, Spain
Prof. Declan Gilheany, University College Dublin, Ireland
Dr. Kai Rossen, Sanofi-Aventis, Germany
Dr. Martin Ernst, BASF, Germany
Prof. Maurizio Benaglia, University of Milan, Italy

Organizing Committee

Prof. Anthony Burke, University of Evora, Portugal
Prof. António Teixeira, University of Evora, Portugal
Prof. Paulo Mendes, University of Evora, Portugal
Prof. José Eduardo Castanheiro, University of Evora, Portugal
Dr. Elisabete Carreiro University of Evora, Portugal
Dr. Carolina Marques, University of Evora, Portugal
Dr. Olívia Furtado, LNEG, Lisbon, Portugal
Luís Fernandes, University of Evora, Portugal

Scientific Program

The conference will be organized into 15 plenary lectures (45 min. each), delivered by a series of internationally recognized speakers from academia and industry, 25 short talks (20 min., selected by the scientific committee), 36 flash talks (about 8 mins, selected by the scientific committee) and two poster sessions with prizes for the best posters and flash talks.

The poster sessions will be divided into three distinct categories; Synthetic Methodology, Catalysis, total or target based synthesis. The scientific committee will select the best posters from each category, and a prize will be awarded to the first author.

For those presenting posters, they will be expected to present them over the two poster session periods, one will be expected to place their poster in their attributed space by lunch-time on the 5th of September and remove them by the end of the conference

Both Wiley-VCH Verlag GmbH & Co. KGaA – A company of John Wiley & Sons, Inc, and Molecules have very kindly agreed to award a textbook (Catalytic Asymmetric Methods: From the Academic Lab to Industrial Processes, Burke and Marques) and a feature paper slot as the prizes for the best flash presentations. Catalysts, Thieme (SynFacts) and Organic & Biomolecular Chemistry (RSC) have kindly agreed to award prizes for the best poster presentations in the different categories.


Key areas

The conference will focus on the following key areas:

  • Total synthesis
  • Synthesis in Medicinal chemistry and chemical biology
  • New reagents, catalysts, strategies and concepts for organic synthesis
  • Biocatalysis in synthesis
  • Organocatalysis
  • Flow-chemistry approaches to the synthesis of key targets
  • Applications of organometallic compounds in synthesis and catalysis
  • Stereoselective synthesis
  • Synthesis and property of functional molecules and organic materials
  • Sustainable and Green synthetic and catalytic methods
  • Process development of key pharmaceutical targets
  • Computational tools for synthesis and catalysis
  • Polymer synthesis

Conference Time Schedule

International Symposium on Synthesis and Catalysis 2017 (ISySyCAT2017)

Plenary Speakers

Prof. Armando Pombeiro "Functionalization of Alkanes: a challenge in catalysis towards organic synthesis",
IST, Portugal


Prof. Janine Cossy "Transition metal catalysis: construction and functionalization of (hetero)cycles",
ESPCI ParisTech, France
Prof. Scott Denmark "Transmetalation in the Suzuki-Miyaura Cross-Coupling Reaction: Mechanistic Insights and Preparative Implications",
University of Illinois, USA
Dr. Stefan Mix "Shortening the Path – Biocatalysis Applications in the Pharmaceutical Industry",
Almac, UK
Prof. Kilian Muñiz "C-H Amination within the Halide Redox Manifold" | SYNTHESIS (Thieme) Best Paper Award Lecture ,
ICIQ, Spain
Dr. Chris Senanayake "Important Asymmetric and Catalytic Transformations for Drug Development",
Boehringer Ingelheim, USA
Prof. Lutz Ackermann "Selectivity Control in C-H Activation",
Georg-August-Universität Göttingen, Germany
Prof. Ian Baxendale "Flow Processes for the Synthesis of ‘Challenging’ Molecules",
University of Durham, UK
Dr. Thomas Schaub "CaRLa – Basic Research for Industrial Applications of Homogeneous Catalysis",
CARLA, Germany
Dr. Ana Cruz, Hovione "Palladium coupling reaction optimization as part of the development of an API synthesis",
Portugal
Prof. Masakatsu Shibasaki "Recent Progress in Cooperative Asymmetric Catalysis",
University of Tokoyo, Japan
Prof. David Milstein "Design and Applications of Sustainable Metal-Catalyzed Reactions",
Weismann Institute, Israel
Prof. Manfred Reetz "Directed Evolution of Stereoselective Enzymes: A Prolific Source of Catalysts for Asymmetric Reactions",
Max-Planck-Institut für Kohlenforschung, Germany
Dr. Carlos Mateos "Continuous flow chemistry: A powerful tool to enable chemistries and scale-up processes",
Eli Lilly, Spain
Prof. Polly Arnold "Exploitation of subtle hydrocarbon interactions in organo-f-block small molecule activation",
Universidade de Edinburgh, UK

Select Speakers

Alkyne and Alkene Functionalization by Visible-Light-Mediated Photoredox Catalysis
Adrian Tlahuext-Aca Westfälische Wilhelms-Universität, Germany
Organocatalysed Asymmetric Synthesis of Sulfur-Containing Heterocycles: from Tetrahydrothiophenes to 1,5-Benzothiazepines
Alessandra Lattanzi Università di Salerno, Italy
Catalytic processes that are suitable for the large scale reduction of aldehydes and ketones
Hans Günter Nedden Johnson Matthey Catalysis and Chiral Technologies, UK
Bio- and chemo-catalysis in the chemistry of lactic acid and PLLA
Ivan Shuklov Rostock, Germany
Enzyme immobilization as the enabler for biocatalysis in flow
Hans-Jürgen Federsel EnginZyme AB, Sweden
Catalysed Stereoselective Synthesis of Deoxyglycosides
Carlos Palo-Nieto University of Bristol, UK
Pd-Catalyzed C-H Functionalization Events Directed by 1,2,3-Triazoles
Arkaitz Correa University of the Basque Country, Spain
Powerful New Umpolung C-C and C-N Bond Forming Reactions via Enolonium Species
Alex M. Szpilman Ariel University, Israel
Syntheses and Structures of Bimetallic Complexes Supported by Flexible Di(imino)pyridine-based Macrocycles
Shaoguang Zhang University of Pennsylvania, USA
Sustainable Catalytic Systems based on Acyl-Functionalized Imidazoles
Isidro M. Pastor University of Alicante, Spain
Bio-inspired Catalysts for Activation of Small Molecules
Mariette M. Pereira University of Coimbra, Portugal
OrthogonalSubstrate-Selective C-H Functionalisation of Organosulphur Compounds Originating from Crude Oil.
Konstantin V. LuzyaninUniversity of Liverpool, UK
Reduction of Carbon Dioxide by Formate Dehydrogenase: Aiming to Develop a Catalyst for Carbon Dioxide Utilization
Luisa Maia Universidade Nova de Lisboa, Portugal
A Metal-Catalyzed Journey To New Azaindole Synthesis
M. Manuel B. Marques Universidade Nova de Lisboa, Portugal
Synthesis of next generation catalysts for C2 + N1 aziridinations from organic azides and alkenes
David. M. Jenkins University of Tennessee, USA
Catalytic Reductions with Manganese N-Heterocyclic Carbenes
Beatriz Royo ITQB, Portugal.
Continuous-flow stereoselective catalytic synthesis of Active pharmaceutical Ingredients in micro- and (3D-printed) meso-reactors
Sergio Rossi Università degli Studi di Milano, Italy
Brønsted Acid Catalyzed Nitrile Synthesis from Aldehydes via Transoximation under Mild Conditions
Kengo HyodoRyukoku University, Japan
Origin of Lewis Acid Induced endo/exo Selectivity Enhancement in the Diels-Alder Reaction: Reduced Steric Penalty for endo
Lawrence M Wolf University of Massachusetts Lowell, Lowell, Massachusetts 01854, USA
Indium(III)-Catalyzed Intramolecular Cycloisomerization Reactions of Alkynes: Synthesis of 2H-Chromenes, Benzo[b]furans and Derivatives
José Pérez Sestelo Universidade da Coruña, Spain
Use of Branched and Dendritic Scaffolds for Controlling Selectivity in Organocatalysis
Moshe PortnoyTel Aviv University, Israel
Designed Aplyronine Warheads for Next-Generation Antibody−Drug Conjugates
Talia Pettigrew University of Cambridge, UK
In situ generation of Gold(I) Nanoparticles as Catalyst of Solventless A3 Coupling Synthesis of Propargylamines
Fernando López-Ortiz University of Almería, Spain
The influence of the porphyrins’ macrocycle and its metal on the type, efficiency and selectivity of catalysis
Mário M.Q. Simões University of Aveiro, Portugal
Rapid access to novel multifunctional spirocyclic cores for drug discovery
P. K. Mykhailiuk Enamine Ltd, Ukarine

Flash Talsk Speakers

Registration

Registration includes:

  • Access to all talks, poster sessions and exhibition booths.
  • Coffee breaks and lunches.
  • Book of abstracts.
  • Conference reception.
  • Conference banquet (with a fine selection of local and regional dishes and wines). The ISySyCat2017 banquet will take place in the spectacular location of the Cinco Quinas restaurante within the confines of the historic Palacio Cadaval dating back over 600 years. This space has been opened up to the public for various functions and boasts of an excellent cuisine. Palacio Cadaval

  • Free-wireless connection throughout the conference.
  • Category Price before July 15th 2017 (€) Price after July 15th2017 (€)
    non-members of the
    Portuguese Chemical Society
    members of the
    Portuguese Chemical Society
    non-members of the
    Portuguese Chemical Society
    members of the
    Portuguese Chemical Society
    Academic 420 380 520 480
    Industrial 610 570 710 670
    Post-docs 340 300 440 400
    Students * 230 190 330 290
    Accompanying Person 150
    Social Program 40 €/per person
    * PhD, MS or other. ** With subscription up to date.

    Non-SPQ members will be offered a free one year membership of the SPQ (till the end of 2017) upon registration with payment, so please register asap to avail of this opportunity (www.spq.pt)

    Payment will be via VISA or bank transfer.

    Abstract submission

    Each registered participant will be entitled to submit up to 2 abstracts, for a poster or an oral presentation. However, only one abstract will be considered for oral or flash presentation.

    The meeting’s official language will be English

    Abstracts should be submitted via the SPQ registration site. Please, log in using the login and the password provided during the registration process and then proceed with "abstract submission". Please use the Microsoft Word file Abstract Template.

    The abstract must not exceed one A4 page. Decision between poster and oral communications will be made by the scientific committee upon evaluation of the submitted abstracts. The abstract file should be saved as follows: name_surname_poster.doc or name_surname_oral.doc (or docx in either case). Each participant can submit up to two abstracts as presenting author, however, only one will be considered for oral communication and this should be indicated on the appropriate form.

    The Deadline for receipt of poster abstracts has been extended until the 20th of June 2017
    The participants will be informed by e-mail message about the acceptance of their contribution and the type of their presentation by June 30th, 2017.

    Accepted abstracts will be published in the Book of Abstracts (only abstracts of registered participants will be included).

    Please make sure your abstract does not contain any spelling or grammar mistakes, as it will be reproduced as submitted.


    Steps for abstract(s) submission Abstract template Personal Area/abstract submission

    Key Dates

    • The deadline for receipt of payment for registration with discount is the 15th July 2017

    • Registration without discount: 31st July 2017

    • The Deadline for receipt of poster/oral abstracts has been extended until the 20th of June 2017 * **


    • * Applicants will be informed about the acceptance of their abstract for a poster or an oral presentation prior to the 30th June 2017.
      ** Abstract submission will involve registration without payment.

    Social Program

    On the afternoon of the 8th of September, you are invited to part-take in a delightful social program. One of the programs includes a coach trip to the famous Carmim Winery followed by a visit to the historic unique mediaeval village of Monsaraz overlooking the beautiful artificial lake known as Alqueva. The other includes a walking guided tour to visit the most exciting historic sites in the town of Évora. Full details on the walking guided tour will be given during the conference.

    CARMIN Reguengos Winery

    This well-known winery was founded in 1970 and is located in the historical town of Reguengos, which is close to the mediaeval village of Monsaraz (which will also be visited) and overlooks the spectacular artificial lake and tourist attraction, Alqueva (which you will also see). Carmim is the largest winery in the Alentejo region, that boasts of being one of the largest in the country and in terms of wine production and bottling one of the most technologically advanced wineries in the whole iberian Peninsula. It is a well-respected brand in Portugal.

    Guided Tour of the Winery

    After a delightful lunch at the renowned Carmim Reguengos winery restaurant (see below for further information), you will be given a ninety minute tour of the whole winery and a unique view of the whole wine production process.
    This will be the ideal time to visit the winery, as it overlaps with the heart of the harvest season, and you will see for yourself the whole process in action, from the delivery of the grapes to the factory, right to the bottling and storage of the wine.
    This tour will terminate with a wine-tasting opportunity, of two classy wines - a red variety (tinto) and a white variety (branco) - chosen specifically for your palate by experts from the Carmim winery. This session will be accompanied by one of the experienced wine tasters from this winery, to give you an appreciation of the hidden secrets of these remarkable wines.

    Monsaraz

    After the visit to the Carmim winery, you will be taken by coach to visit the historically unique medieval village of Monsaraz, which is one of the oldest villages in Portugal. This amazing place, with a very strong sense of medieval days gone by, dates back more than a thousand years. Some of the highlights to be visited, include the parish church which stands accompanied by an unusual 18th century pillory topped by a sphere of the universe, and a church interior containing gilded altars and painted pillars), as well as the granite castle with impressive battlements for eagle-eye views of the houses within the village walls and for the breath-taking landscape of the surrounding countryside. Within its confines, it houses an unusual bullfight arena that is the host to various bull-fight events several times a year. In fact, it is expected that your visit to Monsaraz will coincide with its yearly summer festival, that is expected to be in full swing (so you never know what to expect……). You will also encounter many other small treats along the way.

    Lunch *

    After a welcome drink served with Espumante Monsaraz, lunch will be served and consist of the following tasty dishes:

    • Starters (Patê de Delicias do Mar, olives and a selection of ham and cheese from the region) accompanied by Monsaraz Rosé wine.
    • First dish (Bacalhau assado no forno à posta) accompanied by exclusive Régia Colheita white wine.
    • Second dish (Bochechas de Porco assadas no Forno) accompanied by Monsaraz Reserva Tinto red wine.
    • Desert; accompanied by Vinho Licoroso Carmim, liquor.
    * Persons with dietary restrictions should indicate this on the registration form so that an alternative can be arranged.

    Travel

    The conference organization will place a coach at the disposal of participants to take them to Evora on the evening of the 4th September 2017, the coach will leave the airport after aprox. 9:30 pm. Participants should go to the Meeting Point, at the airport arrivals hall, where they will be met by a member of the organizing committee who will take them to the coach.

    The conference organization will place a coach at the disposal of participants to take them to Evora on the evening of the 4th September 2017. A member of the conference organization will then bring participants to the coach for the trip to Evora. Immediately after the conference closing ceremony on the 8th of September, a coach will take participants back to Lisbon airport. More details will be given later.


    TAP Portugal, as the Official Carrier of the ISySyCat, offers a discount to the participants who book their flight and buy their ticket exclusively through TAP Portugal’s website.

    Additional information concerning the conditions and the required code to proceed further with your booking can be downloaded here.


    The conference will take place in the Colégio Espirito Santo, of the University of Evora, with the following reference: www

    GPS Coordinates: Latitude/longitude: 38.5731/-7.904408333333

    By Car

    From Lisbon (approx. 1-2 hr journey)
    Take the A12 motorway in the direction of Spain, change to A6 motorway in the direction of Evora. www

    From Faro (approx. 3 hr journey)
    Take the A22 motorway in the direction of Lisbon. Change to the IP2 roadway in the direction of Beja and then on the same roadway to Evora. www

    From Spain
    Take the E-90 from Badajoz in the direction of Evora. www

    By Train

    Evora has train connections with a number of key towns and cities. There is a service to Evora from Lisbon (from the Sete Rios Train Station ) running twice in the morning and twice in the evening ( Refer). The trip takes about 1 and a half hours. Tickets can be bought on-line.
    There is a metro connection at Lisbon airport that will take you to the train station at Sete Rios.

    By Bus

    Evora has bus connections with a number of key towns and cities, including Faro ( Rede-Expressos). Tickets can be bought on-line. If you are coming from Lisbon airport you can take the metro to Sete Rios bus station (you get out at the Jardin Zoologico metro station). The trip takes about 2 hours.

    Accommodation

    For the duration of the conference, the University of Evora, has made available to delegates a limited number of rooms (for 2 or 3 people on a sharing basis) close to the conference venue. The cost will be 15€/night, which includes a light continental breakfast in the University canteen in the morning. Please contact the staff at daa@sas.uevora.pt for further details. University residential


    Here is a selection of hotels/residences that should suit all pockets. When making your reservation or your enquiry, please mention ISySyCat2017 for the conference discount.

    M´AR De AR Aqueduto ***** reservas@mardearhotels.com
    M'AR De AR Muralhas **** reservas@mardearhotels.com
    Albergaria do Calvário **** hotel@adcevora.com
    Vitória Stone Hotel **** book@vitoriastonehotel.com
    Evora Hotel **** reservas@evorahotel.pt
    Moov Hotel Evora *** evora@hotelmoov.com
    Hotel íbis Évora *** H1708@accor.com
    Santa-Clara Best Western *** reservas@hotelsantaclara.pt

    Olive Hotel (Eborim) **** evora.reservas@luxhotels.pt
    Hotel Dom Fernando reservas@hoteldomfernando.com
    Old Evora Hostel oldevorahostel@gmail.com
    Stayinn Ale-Hop stayinn.alehop@gmail.com
    Evorainn evorainn@gmail.com
    Pousada de Juventude de Évora evora@movijovem.pt

    General information

    Insurance:
    All conference attendees are advised to arrange private travel insurance. The conference organizers and committee accept no liability for personal accidents or damage to property. The organizing committee of ISySyCat2017 reserves the right to amend and/or alter the conference program without prior notice.

    Electricity:
    The voltage in Lisbon is The local current is 220 AC and the connection is made by a two-pin plug. Traveller's from the US will require a voltage converter. Travellers from the UK will require a plug adapter and this is best bought in the UK as they are hard to find in Lisbon (can try at the Lisbon airport).

    Currency, Banks and Post Offices:
    The national currency in Portugal is Euro. Banks are open from Monday to Friday between 8.30 am and 3 pm. Post offices are usually open between 8.30 am and 6 pm. Exchange houses operate everyday between 9 am and 1 pm and from 2 pm to 7 pm.


    Time Zone:
    The time zone in Portugal is GMT.

    Water:
    Tap water in Portugal is drinking water!

    Going out in Evora:
    With your conference material you will find a city map and a brochure of Evora with lots of necessary information.

    Climate:
    In early September, the temperature in Evora is on average 30ºC (the nights are hot) rain is very unlikely.

    CAR PARKING

    The University car-park, in front of the conference venue will be available for participants with cars to park. The entrance to the car-park is via Rua Cardeal Rei street, which you enter via Rua Duques de Cadaval street (ONE-WAY TRAFFIC SYSTEM). The car-park generally shuts at midnight.

    Contacts Us

    SPQ - Sociedade Portuguesa de Química - Secretariat/Payments/Billing

      Av. da República, 45 - 3º Esq.
      1050 - 187 Lisboa
      Portugal

      (+351) 217 934 637
    eventos@spq.pt

    General Information - Organization/Program
    isysycat2017@chemistry.pt

    SPONSORSHIP AND EXHIBITING

    To promote and advertise your company we have a number of interesting packages available for you at competitive prices. Please contact Anthony Burke isysycat2017@chemistry.pt for further details.

    We thank the following companies and organizations for their kind sponsorship and support of ISySyCat2017.

    Platinum (Catalyst) Sponsor


    Gold Sponsor


    Silver Sponsor



    Media Partner


    Molecules has kindly offered to sponsor a feature paper slot to publish free of charge for the best flash presentation



    Catalysts has kindly offered a prize of 500 CHF for the best poster presentation in the area of catalysis.



    ChemCatCat will publish a special edition in 2018 that will cover both ISySyCat2015 and ISySyCat2017 and the work of various Portuguese groups active in the area of catalysis